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Description
Mounjaro or Zepbound: helpful for weight loss but hell on your skin? , Getting a rash at your injection site? Youre not the only one., Typically happens around 10mg dose increase, Looks like GLP 1 medications mentioned by the WHO. The World Health Organization released its first global guideline on using GLP 1 medicines for obesity, emphasizing safe, appropriate, provider guided care. DM for consultation #GLP1 #WHOGuidelines # Beyond the Scale: Your Guide to GLP 1s Tufts Medicine hers glp 1 microdosing Microdosing GLP 1 Drugs: What To Know Mechanism of action of GLP 1 [25]. Download Scientific Diagram Glucagon like peptide 1 medicines and cancer Nature Cancer
![Mechanism of action of GLP-1 [25]. | Download Scientific Diagram](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png "Mechanism of action of GLP-1 [25]. | Download Scientific Diagram")
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Best in 7 days
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Best in 7 days
4.2 ★★★★★
Based on 298 reviews
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Product Reviews
★★★★★ 5
Look great for dress up up casual
Size: 13, Color: Black Leather/Optic White
I wear them every day for work. They are comfortable and light. I will say I was frustrated with the crease in the top that started the first time I wore them but other than that they are a great pair of shoes.
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Reviewed in the United States on March 22, 2026
★★★★★ 5
RETRO STYLING, VERY COMFORTABLE; QUALITY MATERIAL
Size: 11, Color: Black Leather/Black
VERY COMFORTABLE AND STYLISH PAIR OF SHOES; OLD FASHIONED STYLING; VERY NICE; WHEN THESE WEAR OUT, I WILL CERTAINLY BUY ANOTHER PAIR!!
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Reviewed in the United States on April 15, 2026
★★★★★ 5
Great shoe
Size: 11.5 Wide, Color: Tan Leather Burnished
Very comfortable business casual shoe. Looks professional, yet stylish
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Reviewed in the United States on April 29, 2026
★★★★★ 4
Hard to Beat for the Price
Size: 10 Wide, Color: Tan Leather Burnished
I purchased these for a business trip to Italy and wore them daily for the two weeks that I was there, during which I walked extensively. For me, there was a break-in period of a few days; before it loosens up, it will bite your heel, so I recommend wearing bandages or heel pads initially. Following the break-in, it's a very comfortable shoe and has served me well.
I purchased a wide, and for this shoe, I found the width agreeable; in my experience, Cole Haan wide widths tend to be hit or miss (i.e., a wide is sometimes not all that wide). In terms of durability, I would not expect these to remain in good condition for more than a year if you wear them daily. The leather is not of high quality, but it's acceptable for the price. Expect them to crease very quickly if not using shoe trees. That doesn't bother me, but I know some find it objectionable.
All in all, I like them and would buy them again. It's a comfortable alternative to traditional dress shoes for the office and works equally well for casual wear. Most higher quality options cost at least two or three times as much, and many are unavailable in a wide.
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Reviewed in the United States on December 16, 2025
★★★★★ 5
My favorite shoes
Size: 14 Wide, Color: White Leather
I’ve probably purchased like 40 pairs of these shoes or more. By far my favorite white sneaker. I have a large foot so the bigger sizes are appreciated. They’re versatile, literally go with anything and they are true to size. At a certain point they start to show wear and you can’t dress them up, but they last as a regular sneaker for a long time afterwards. I try to nab them on sale when they drop to $50-$70, absolute steal at that price point.
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Reviewed in the United States on May 9, 2026
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